B. AUBREY SCHNEIDER, Sc.D.: (1912-1960)

Aptamer therapy for SCD?

In this issue of Blood, Gutsaeva et al describe an aptamer with high affinity for murine P-selectin and its efficacy in preventing vaso-occlusion in a mouse sickle cell disease (SCD) model.1 Each year, more than 200 000 children are born with SCD,2 yet there is a paucity of treatment options available for sufferers.3 The disease is caused by homozygous expression of a mutation in the beta globi...

John Aubrey and the realm of learning

qualifications to write these books. But he has an attractive if rather journalistic style, the data he presents are fully documented, and he includes useful appendices with additional technical information. In the first title the author has accumulated his evidence by detailed and extensive research, including encounters with addicts, pushers, and police. He examines all aspects of the drug an...

Genome Sequence of Zymomonas mobilis subsp. mobilis NRRL B-1960

Zymomonas mobilis subsp. mobilis is an efficient ethanol producer with application for industrial production of biofuel. To supplement existing Z. mobilis genomic resources and to facilitate genomic research, we used Oxford Nanopore and Illumina sequencing to assemble the complete genome of the beer spoilage isolate Z. mobilis subsp. mobilis strain NRRL B-1960.

Schneider 27-5

Treatment options for ductal adenocarcinoma of the pancreas are limited by early lymphatic spread, but the lymphatic vessels in pancreatic carcinoma have not been studied to date. Here, we present a histomorphological analysis of lymphatic vessels in pancreatic cancer resection specimens. Both intratumoral and peritumoral tissue were devoid of active lymphangiogenesis. Intratumoral lymphatics w...

Michael Abercrombie (1912-1979).